MexDrugs is a database of genetic interactions that were found to be mutually exclusive in multi-'omic data from The Cancer Genome Atlas using the algorithm MexD.
MexD uses matched somatic mutation, copy number variance and methylation data from The Cancer Genome Atlas, together with drug information from the Druggable genome databank, to identify cancer-associated genes that are mutually exclusive with genes that are inhibited by existing drugs. In some cases these genetic interactions may arise because the genes are synthetically lethal.
Disclaimer: The information provided is for research purposes only and is not intended as medical advice.
It should not be used to diagnose, treat, or replace professional medical consultation.
MexDrugs Data is available for the cancers shown in the navigation bar at the top of the page