MexDrugs - A mutually exclusive genetic interaction database
MexDrugs is a database of genetic interactions that are predicted to be mutually exclusive in the cancer tissue of choice by the algorithm MexD. MexD uses matched somatic mutation, copy number variance and methylation data from The Cancer Genome Atlas, together with drug information from the Druggable genome databank, to predict cancer-associated genes that may be synthetically lethal with genes that are inhibited by existing drugs.
Prostate cancer
Within prostate cancer there are 14 drugs that inhibit genes predicted to be mutually exclusive. These are listed in the drop-down box below, and link to the pages giving MexDrugs predictions.